No, it is not recommended to mix water-based inks and plastisol inks. Water-based inks and plastisol inks are designed to work differently, and their chemical compositions are not compatible with each other.

Water-based inks are made from water-soluble pigments, while plastisol inks are made from PVC particles suspended in a plasticiser. When mixed together, the water-based ink can cause the plastisol to curdle or coagulate, ruining the print and potentially damaging the printing equipment.

If you need to use both types of inks in a print job, it is best to use them separately and not try to mix them together. It is also essential to clean your equipment thoroughly between using water-based inks and plastisol inks to prevent any contamination or mixing of the inks.